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MR-guided focused ultrasound with continuous sonication along a spiral trajectory of the focal point has the advantage to deliver a uniform thermal dose within the treated volume. The question of the thermal safety in neighbouring tissue behind and

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US Patent for Anti-myostatin antibodies, polypeptides ...

The disclosure provides anti-myostatin antibodies and methods of making and using the same. Nucleic acids encoding the anti-myostatin antibodies and host cells comprising the nucleic acids are also provided. The anti-myostatin antibodies have uses that include treating a muscle wasting disease, reducing body fat accumulation, and increasing mass and strength of muscle tissue.

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(PDF) MRI-Guided Focused Ultrasound applied with ...

MR-guided focused ultrasound with continuous sonication along a spiral trajectory of the focal point has the advantage to deliver a uniform thermal dose within the treated volume. The question of the thermal safety in neighbouring tissue behind and

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The disclosure provides anti-myostatin antibodies and methods of making and using the same. Nucleic acids encoding the anti-myostatin antibodies and host cells comprising the nucl

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MR-guided focused ultrasound with continuous sonication along a spiral trajectory of the focal point has the advantage to deliver a uniform thermal dose within the treated volume. The question of the thermal safety in neighbouring tissue behind and

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US Patent for Anti-myostatin antibodies, polypeptides ...

The disclosure provides anti-myostatin antibodies and methods of making and using the same. Nucleic acids encoding the anti-myostatin antibodies and host cells comprising the nucleic acids are also provided. The anti-myostatin antibodies have uses that include treating a muscle wasting disease, reducing body fat accumulation, and increasing mass and strength of muscle tissue.

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ANTI-C5 ANTIBODIES HAVING IMPROVED PHARMACOKINETICS ...

1. 1-36. (canceled) 37. An isolated antibody, or antigen-binding fragment thereof, that: (a) binds to complement component human C5; (b) inhibits the cleavage of C5 into fragments C5a and C5b; and (c) comprises: (i) a heavy chain CDR1 comprising the amino acid sequence depicted in SEQ ID NO:23, (ii) a heavy chain CDR2 comprising the amino acid sequence depicted in SEQ ID NO:19, (iii) a heavy ...

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ANTI-C5 ANTIBODIES HAVING IMPROVED PHARMACOKINETICS ...

1. 1-36. (canceled) 37. An isolated antibody, or antigen-binding fragment thereof, that: (a) binds to complement component human C5; (b) inhibits the cleavage of C5 into fragments C5a and C5b; and (c) comprises: (i) a heavy chain CDR1 comprising the amino acid sequence depicted in SEQ ID NO:23, (ii) a heavy chain CDR2 comprising the amino acid sequence depicted in SEQ ID NO:19, (iii) a heavy ...

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